Гены, связанные с развитием сердечно-сосудистых заболеваний
Ключевые слова:
атеросклероз, артериальная гипертензия, инфаркт миокарда, ишемическая болезнь сердца, метаболический синдром, ген, диагностика.Аннотация
Проведен поиск генов-кандидатов, связанных с развитием сердечно-сосудистых заболеваний, таких как атеросклероз, артериальная гипертензия, инфаркт миокарда, ишемическая болезнь сердца, метаболический синдром. Созданные базы данных по генам, связанных с развитием данных заболеваний проанализированы в сравнительном аспекте. Показано, что некоторые из генов участвуют в развитии всех указанных выше заболеваниях (AGTR1, ALDH2, APOE, ICAM1, IGF1, LPL, MTHFR, PON1, SERPINE1, TGFB1, VEGFA). Некоторые гены участвуют в развитии только одной формы сердечно-сосудистых заболеваний (ACSL1, ADTRP, AKT1, ALMS1, ANXA5, AQP2, AR, ATP2B1, CASZ1, CDH13, CELSR2, CFTR, CTSL, CUL7, DAP, DYRK1B, FIGN, FN1, FOS, FTO, GSN, HDAC9, ICOS, INPPL1, JAK2, LPIN1, MKKS, EDD4L, NFE2L2, PRL, SMTN, SOCS1, SOCS3, UMOD, WNT5A). Полученные результаты служат основой для выявления генов, экспрессия которых зависит от действия microRNA. Исследования по выявлению ассоциаций генов-кандидатов как мишеней microRNA имеют большое значение, поскольку низкомолекулярные RNA селективно регулируют экспрессию практически всех генов человека и могут вызвать как заболевание, так и использоваться в терапии и диагностике этих заболеваний.
Библиографические ссылки
Литература
1 Grundy S.M. Obesity, metabolic syndrome, and cardiovascular disease // Journal of Clinical Endocrinology and Metabolism.– 2004.- 89(6). – Р.2595-600.
2 Erickson S.R., Spoutz P., Dorsch M., Bleske B. Cardiovascular risk and treatment for adults with intellectual or developmental disabilities // The International Journal of Cardiology.– 2016.- 5.221.– Р.371-375.
3 Tong D.C., Wilson A.M., Layland J. Novel risk factors for acute coronary syndromes and emerging therapies // The International Journal of Cardiology.-2016.- 25;220.- Р.815-824.
4 Ahmadi A., Stone G.W., Leipsic J., Shaw L.J., Villines T.C., Kern M.J., Hecht H., Erlinge D., Ben-Yehuda O., Maehara A., Arbustini E., Serruys P., Garcia-Garcia H.M., Narula J. Prognostic Determinants of Coronary Atherosclerosis in Stable Ischemic Heart Disease: Anatomy, Physiology, or Morphology? // Circulation Research, 2016.- 8.- 119(2).- Р.317-29.
5 Guha A., Amione-Guerra J., Park M.H. Epidemiology of Pulmonary Hypertension in Left Heart Disease // Progress in Cardiovascular Diseases.- 2016.- 8.- Р.30053-6.
6 Grinnan D., Farr G., Fox A., Sweeney L. The Role of Hyperglycemia and Insulin Resistance in the Development and Progression of Pulmonary Arterial, Hypertension // Journal of Diabetes Research.- 2016.- Р.2481659.
7 Villa A.D., Sammut E., Nair A., Rajani R., Bonamini R., Chiribiri A. Coronary artery anomalies overview: The normal and the abnormal // World Journal of Radiology. 2016.- 28;8(6).- Р.537-55.
8 Trenkwalder T., Kessler T., Schunkert H., Erdmann J. Genetics of coronary artery disease: Short people at risk? // Expert Review of Cardiovascular Therapy.- 2015.- 13(11).- Р.1169-72.
9 Arbour L., Asuri S., Whittome B., Polanco F., Hegele R. The Genetics of Cardiovascular Disease in Canadian and International Aboriginal Populations // Canadian Journal Of Cardiology.- 2015.- 31(9).- Р.1094-115.
10 Brænne I., Civelek M., Vilne B., Di. Narzo A, Johnson A.D., Zhao Y., Reiz B., Codoni V., Webb T.R., Foroughi Asl. H, Hamby S.E., Zeng L., Trégouët D.A., Hao K., Topol E.J., Schadt E.E., Yang X., Samani N.J., Björkegren J.L., Erdmann J., Schunkert H., Lusis A.J.; Leducq Consortium CAD Genomics Prediction of Causal Candidate Genes in Coronary Artery Disease Loci // Arteriosclerosis, Thrombosis, and Vascular Biology.- 2015.- 35(10).- Р.2207-17.
11 Hamrefors V. Common genetic risk factors for coronary artery disease: new opportunities for prevention? // Clinical Physiology And Functional Imaging.- 2015.- Р.17.
12 Cole C.B., Nikpay M., Stewart A.F., Mc.Pherson R. Increased genetic risk for obesity in premature coronary artery disease // European Journal of Human Genetics.- 2016.- 24(4).- Р.587-91.
13 Yamada Y., Matsui K., Takeuchi I., Fujimaki T. Association of genetic variants with coronary artery disease and ischemic stroke in a longitudinal population-based genetic epidemiological study study // Biomedical reports. – 2015.- 3(3).- P.413-419.
14 Ozaki K., Tanaka T. Molecular genetics of coronary artery disease // Journal of Human Genetics.- 2016.- 61(1).- р.71-7.
15 Neelankavil J., Rau C.D., Wang Y. The Genetic Basis of Coronary Artery Disease and Atrial Fibrillation: A Search for Disease Mechanisms and Therapeutic Targets // Journal of Cardiothoracic and Vascular Anesthesia.- 2015.- 29(5).- Р.1328-32.
16 Hernesniemi J.A., Lyytikäinen L.P., Oksala N., Seppälä I., Kleber M.E., Mononen N., März W., Mikkelsson J., Pessi T., Louhelainen A.M., Martiskainen M., Nikus K., Klopp N., Waldenberger M., Illig T., Kähönen M., Laaksonen R., Karhunen P.J., Lehtimäki T. Predicting sudden cardiac death using common genetic risk variants for coronary artery disease // The European Heart Journal.- 2015.- 7;36(26).- Р.1669-75.
17 Cheng Y., An B., Jiang M., Xin Y., Xuan S. Association of Tumor Necrosis Factor-alpha Polymorphisms and Risk of Coronary Artery Disease in Patients With Non-alcoholic Fatty Liver Disease // Hepatitis Monthly.- 2015.- 31.- 15(3).- P.26818.
18 Liao B., Cheng K., Dong S., Liu H., Xu Z. Effect of apolipoprotein A1 genetic polymorphisms on lipid profiles and the risk of coronary artery disease // Diagnostic Pathology.- 2015.- 16;10.- Р.102.
19 Arslan S., Korkmaz Ö., Özbilüm N., Berkan Ö. Association between NF-κBI and NF-κBIA polymorphisms and coronary artery disease // Biomedical reports.- 2015.- 3(5).- Р.736-740.
20 Ahmadi Z., Senemar S., Toosi S., Radmanesh S. The Association of Lipoprotein Lipase Genes, HindIII and S447X Polymorphisms With Coronary Artery Disease in Shiraz City // Journal of Thoracic and Cardiovascular Surgery.- 2015.- 7(2).- Р.63-7.
21 Иващенко А.Т., Атамбаева Ш.А., Ниязова Р.Е., Пинский И.В. Гены, связанные с развитием ишемической болезни сердца // Вестник КазНУ, серия биологическая.- 2015.- №3 (65). - C. 100-108.
22 Иващенко А.Т., Атамбаева Ш.А., Ниязова Р.Е., Пинский И.В. Гены, связанные с развитием инфаркта миокарда // Вестник КазНУ, серия биологическая.- 2015.- №3 (65). – P. 124-132.
References
1 Grundy SM (2004) Obesity, metabolic syndrome, and cardiovascular disease, Journal of Clinical Endocrinology and Metabolism, 89(6):2595-600.
2 Erickson SR, Spoutz P, Dorsch M, Bleske B (2016) Cardiovascular risk and treatment for adults with intellectual or developmental disabilities, The International Journal of Cardiology, 5;221:371-375. DOI: 10.1016/j.ijcard.2016.07.044.
3 Tong DC, Wilson AM, Layland J (2016) Novel risk factors for acute coronary syndromes and emerging therapies, The International Journal of Cardiology, 25;220:815-824. DOI: 10.1016/j.ijcard.2016.06.148.
4 Ahmadi A, Stone GW, Leipsic J, Shaw LJ, Villines TC, Kern MJ, Hecht H, Erlinge D, Ben-Yehuda O, Maehara A, Arbustini E, Serruys P, Garcia-Garcia HM, Narula J (2016) Prognostic Determinants of Coronary Atherosclerosis in Stable Ischemic Heart Disease: Anatomy, Physiology, or Morphology? Circulation Research, 8;119(2):317-29. DOI: 10.1161/CIRCRESAHA.116.308952.
5 Guha A, Amione-Guerra J, Park MH (2016) Epidemiology of Pulmonary Hypertension in Left Heart Disease, Progress in Cardiovascular Diseases, 8. pii: S0033-0620(16)30053-6. DOI: 10.1016/j.pcad.2016.07.001.
6 Grinnan D, Farr G, Fox A, Sweeney L (2016) The Role of Hyperglycemia and Insulin Resistance in the Development and Progression of Pulmonary Arterial, Hypertension, Journal of Diabetes Research, 2016:2481659. DOI: 10.1155/2016/2481659.
7 Villa AD, Sammut E, Nair A, Rajani R, Bonamini R, Chiribiri A (2016) Coronary artery anomalies overview: The normal and the abnormal, World Journal of Radiology, 28;8(6):537-55. DOI: 10.4329/wjr.v8.i6.537.
8 Trenkwalder T, Kessler T, Schunkert H, Erdmann J (2015) Genetics of coronary artery disease: Short people at risk? Expert Review of Cardiovascular Therapy, 13(11):1169-72. DOI: 10.1586/14779072.2015.1094377.
9 Arbour L, Asuri S, Whittome B, Polanco F, Hegele R (2015) The Genetics of Cardiovascular Disease in Canadian and International Aboriginal Populations, Canadian Journal Of Cardiology, 31(9):1094-115. DOI: 10.1016/j.cjca.2015.07.005.
10 Brænne I, Civelek M, Vilne B, Di Narzo A, Johnson AD, Zhao Y, Reiz B, Codoni V, Webb TR, Foroughi Asl H, Hamby SE, Zeng L, Trégouët DA, Hao K, Topol EJ, Schadt EE, Yang X, Samani NJ, Björkegren JL, Erdmann J, Schunkert H, Lusis AJ; Leducq Consortium CAD Genomics (2015) Prediction of Causal Candidate Genes in Coronary Artery Disease Loci, Arteriosclerosis, Thrombosis, and Vascular Biology, 35(10):2207-17. DOI: 10.1161/ATVBAHA.115.306108.
11 Hamrefors V (2015) Common genetic risk factors for coronary artery disease: new opportunities for prevention? Clinical Physiology And Functional Imaging, 17. DOI: 10.1111/cpf.12289.
12 Cole CB, Nikpay M, Stewart AF, McPherson R (2016) Increased genetic risk for obesity in premature coronary artery disease, European Journal of Human Genetics, 24(4):587-91. DOI: 10.1038/ejhg.2015.162.
13 Yamada Y, Matsui K, Takeuchi I, Fujimaki T (2015) Association of genetic variants with coronary artery disease and ischemic stroke in a longitudinal population-based genetic epidemiological study study, Biomedical reports, 3(3), p.413-419.
14 Ozaki K, Tanaka T (2016) Molecular genetics of coronary artery disease, Journal of Human Genetics, 61(1):71-7. DOI: 10.1038/jhg.2015.70.
15 Neelankavil J, Rau CD, Wang Y (2015) The Genetic Basis of Coronary Artery Disease and Atrial Fibrillation: A Search for Disease Mechanisms and Therapeutic Targets, Journal of Cardiothoracic and Vascular Anesthesia, 29(5):1328-32. DOI: 10.1053/j.jvca.2015.01.031. Epub 2015 Jan 23.
16 Hernesniemi JA, Lyytikäinen LP, Oksala N, Seppälä I, Kleber ME, Mononen N, März W, Mikkelsson J, Pessi T, Louhelainen AM, Martiskainen M, Nikus K, Klopp N, Waldenberger M, Illig T, Kähönen M, Laaksonen R, Karhunen PJ, Lehtimäki T (2015) Predicting sudden cardiac death using common genetic risk variants for coronary artery disease, The European Heart Journal, 7;36(26):1669-75. DOI: 10.1093/eurheartj/ehv106.
17 Cheng Y, An B, Jiang M, Xin Y, Xuan S (2015) Association of Tumor Necrosis Factor-alpha Polymorphisms and Risk of Coronary Artery Disease in Patients With Non-alcoholic Fatty Liver Disease, Hepatitis Monthly, 31.15(3), p.26818.
18 Liao B, Cheng K, Dong S, Liu H, Xu Z (2015) Effect of apolipoprotein A1 genetic polymorphisms on lipid profiles and the risk of coronary artery disease, Diagnostic Pathology, 16;10:102. DOI: 10.1186/s13000-015-0328-7.
19 Arslan S, Korkmaz Ö, Özbilüm N, Berkan Ö (2015) Association between NF-κBI and NF-κBIA polymorphisms and coronary artery disease, Biomedical reports, 3(5):736-740.
20 Ahmadi Z, Senemar S, Toosi S, Radmanesh S (2015) The Association of Lipoprotein Lipase Genes, HindIII and S447X Polymorphisms With Coronary Artery Disease in Shiraz City, Journal of Thoracic and Cardiovascular Surgery, 7(2):63-7. DOI: 10.15171/jcvtr.2015.14.
21 Ivashchenko A, Atambayeva S, Niyazova R, Pinsky I (2015) Genes associated with the development of coronary heart disease. Vestnik KazNU, biological series [Geny svyazannye s razvitiem ishemicheskoi bolezni serdtca. Vestnik KazNU, biologicheskaya seriya] 3(65):100-108. (In Russian).
22 Ivashchenko A, Atambayeva S, Niyazova R, Pinsky I (2015) Genes associated with the development of myocardial infarction. Vestnik KazNU, biological series [Geny svyazannye s razvitiem infarcta miocarda. Vestnik KazNU, biologicheskaya seriya] 3(65): 124-132. (In Russian).
1 Grundy S.M. Obesity, metabolic syndrome, and cardiovascular disease // Journal of Clinical Endocrinology and Metabolism.– 2004.- 89(6). – Р.2595-600.
2 Erickson S.R., Spoutz P., Dorsch M., Bleske B. Cardiovascular risk and treatment for adults with intellectual or developmental disabilities // The International Journal of Cardiology.– 2016.- 5.221.– Р.371-375.
3 Tong D.C., Wilson A.M., Layland J. Novel risk factors for acute coronary syndromes and emerging therapies // The International Journal of Cardiology.-2016.- 25;220.- Р.815-824.
4 Ahmadi A., Stone G.W., Leipsic J., Shaw L.J., Villines T.C., Kern M.J., Hecht H., Erlinge D., Ben-Yehuda O., Maehara A., Arbustini E., Serruys P., Garcia-Garcia H.M., Narula J. Prognostic Determinants of Coronary Atherosclerosis in Stable Ischemic Heart Disease: Anatomy, Physiology, or Morphology? // Circulation Research, 2016.- 8.- 119(2).- Р.317-29.
5 Guha A., Amione-Guerra J., Park M.H. Epidemiology of Pulmonary Hypertension in Left Heart Disease // Progress in Cardiovascular Diseases.- 2016.- 8.- Р.30053-6.
6 Grinnan D., Farr G., Fox A., Sweeney L. The Role of Hyperglycemia and Insulin Resistance in the Development and Progression of Pulmonary Arterial, Hypertension // Journal of Diabetes Research.- 2016.- Р.2481659.
7 Villa A.D., Sammut E., Nair A., Rajani R., Bonamini R., Chiribiri A. Coronary artery anomalies overview: The normal and the abnormal // World Journal of Radiology. 2016.- 28;8(6).- Р.537-55.
8 Trenkwalder T., Kessler T., Schunkert H., Erdmann J. Genetics of coronary artery disease: Short people at risk? // Expert Review of Cardiovascular Therapy.- 2015.- 13(11).- Р.1169-72.
9 Arbour L., Asuri S., Whittome B., Polanco F., Hegele R. The Genetics of Cardiovascular Disease in Canadian and International Aboriginal Populations // Canadian Journal Of Cardiology.- 2015.- 31(9).- Р.1094-115.
10 Brænne I., Civelek M., Vilne B., Di. Narzo A, Johnson A.D., Zhao Y., Reiz B., Codoni V., Webb T.R., Foroughi Asl. H, Hamby S.E., Zeng L., Trégouët D.A., Hao K., Topol E.J., Schadt E.E., Yang X., Samani N.J., Björkegren J.L., Erdmann J., Schunkert H., Lusis A.J.; Leducq Consortium CAD Genomics Prediction of Causal Candidate Genes in Coronary Artery Disease Loci // Arteriosclerosis, Thrombosis, and Vascular Biology.- 2015.- 35(10).- Р.2207-17.
11 Hamrefors V. Common genetic risk factors for coronary artery disease: new opportunities for prevention? // Clinical Physiology And Functional Imaging.- 2015.- Р.17.
12 Cole C.B., Nikpay M., Stewart A.F., Mc.Pherson R. Increased genetic risk for obesity in premature coronary artery disease // European Journal of Human Genetics.- 2016.- 24(4).- Р.587-91.
13 Yamada Y., Matsui K., Takeuchi I., Fujimaki T. Association of genetic variants with coronary artery disease and ischemic stroke in a longitudinal population-based genetic epidemiological study study // Biomedical reports. – 2015.- 3(3).- P.413-419.
14 Ozaki K., Tanaka T. Molecular genetics of coronary artery disease // Journal of Human Genetics.- 2016.- 61(1).- р.71-7.
15 Neelankavil J., Rau C.D., Wang Y. The Genetic Basis of Coronary Artery Disease and Atrial Fibrillation: A Search for Disease Mechanisms and Therapeutic Targets // Journal of Cardiothoracic and Vascular Anesthesia.- 2015.- 29(5).- Р.1328-32.
16 Hernesniemi J.A., Lyytikäinen L.P., Oksala N., Seppälä I., Kleber M.E., Mononen N., März W., Mikkelsson J., Pessi T., Louhelainen A.M., Martiskainen M., Nikus K., Klopp N., Waldenberger M., Illig T., Kähönen M., Laaksonen R., Karhunen P.J., Lehtimäki T. Predicting sudden cardiac death using common genetic risk variants for coronary artery disease // The European Heart Journal.- 2015.- 7;36(26).- Р.1669-75.
17 Cheng Y., An B., Jiang M., Xin Y., Xuan S. Association of Tumor Necrosis Factor-alpha Polymorphisms and Risk of Coronary Artery Disease in Patients With Non-alcoholic Fatty Liver Disease // Hepatitis Monthly.- 2015.- 31.- 15(3).- P.26818.
18 Liao B., Cheng K., Dong S., Liu H., Xu Z. Effect of apolipoprotein A1 genetic polymorphisms on lipid profiles and the risk of coronary artery disease // Diagnostic Pathology.- 2015.- 16;10.- Р.102.
19 Arslan S., Korkmaz Ö., Özbilüm N., Berkan Ö. Association between NF-κBI and NF-κBIA polymorphisms and coronary artery disease // Biomedical reports.- 2015.- 3(5).- Р.736-740.
20 Ahmadi Z., Senemar S., Toosi S., Radmanesh S. The Association of Lipoprotein Lipase Genes, HindIII and S447X Polymorphisms With Coronary Artery Disease in Shiraz City // Journal of Thoracic and Cardiovascular Surgery.- 2015.- 7(2).- Р.63-7.
21 Иващенко А.Т., Атамбаева Ш.А., Ниязова Р.Е., Пинский И.В. Гены, связанные с развитием ишемической болезни сердца // Вестник КазНУ, серия биологическая.- 2015.- №3 (65). - C. 100-108.
22 Иващенко А.Т., Атамбаева Ш.А., Ниязова Р.Е., Пинский И.В. Гены, связанные с развитием инфаркта миокарда // Вестник КазНУ, серия биологическая.- 2015.- №3 (65). – P. 124-132.
References
1 Grundy SM (2004) Obesity, metabolic syndrome, and cardiovascular disease, Journal of Clinical Endocrinology and Metabolism, 89(6):2595-600.
2 Erickson SR, Spoutz P, Dorsch M, Bleske B (2016) Cardiovascular risk and treatment for adults with intellectual or developmental disabilities, The International Journal of Cardiology, 5;221:371-375. DOI: 10.1016/j.ijcard.2016.07.044.
3 Tong DC, Wilson AM, Layland J (2016) Novel risk factors for acute coronary syndromes and emerging therapies, The International Journal of Cardiology, 25;220:815-824. DOI: 10.1016/j.ijcard.2016.06.148.
4 Ahmadi A, Stone GW, Leipsic J, Shaw LJ, Villines TC, Kern MJ, Hecht H, Erlinge D, Ben-Yehuda O, Maehara A, Arbustini E, Serruys P, Garcia-Garcia HM, Narula J (2016) Prognostic Determinants of Coronary Atherosclerosis in Stable Ischemic Heart Disease: Anatomy, Physiology, or Morphology? Circulation Research, 8;119(2):317-29. DOI: 10.1161/CIRCRESAHA.116.308952.
5 Guha A, Amione-Guerra J, Park MH (2016) Epidemiology of Pulmonary Hypertension in Left Heart Disease, Progress in Cardiovascular Diseases, 8. pii: S0033-0620(16)30053-6. DOI: 10.1016/j.pcad.2016.07.001.
6 Grinnan D, Farr G, Fox A, Sweeney L (2016) The Role of Hyperglycemia and Insulin Resistance in the Development and Progression of Pulmonary Arterial, Hypertension, Journal of Diabetes Research, 2016:2481659. DOI: 10.1155/2016/2481659.
7 Villa AD, Sammut E, Nair A, Rajani R, Bonamini R, Chiribiri A (2016) Coronary artery anomalies overview: The normal and the abnormal, World Journal of Radiology, 28;8(6):537-55. DOI: 10.4329/wjr.v8.i6.537.
8 Trenkwalder T, Kessler T, Schunkert H, Erdmann J (2015) Genetics of coronary artery disease: Short people at risk? Expert Review of Cardiovascular Therapy, 13(11):1169-72. DOI: 10.1586/14779072.2015.1094377.
9 Arbour L, Asuri S, Whittome B, Polanco F, Hegele R (2015) The Genetics of Cardiovascular Disease in Canadian and International Aboriginal Populations, Canadian Journal Of Cardiology, 31(9):1094-115. DOI: 10.1016/j.cjca.2015.07.005.
10 Brænne I, Civelek M, Vilne B, Di Narzo A, Johnson AD, Zhao Y, Reiz B, Codoni V, Webb TR, Foroughi Asl H, Hamby SE, Zeng L, Trégouët DA, Hao K, Topol EJ, Schadt EE, Yang X, Samani NJ, Björkegren JL, Erdmann J, Schunkert H, Lusis AJ; Leducq Consortium CAD Genomics (2015) Prediction of Causal Candidate Genes in Coronary Artery Disease Loci, Arteriosclerosis, Thrombosis, and Vascular Biology, 35(10):2207-17. DOI: 10.1161/ATVBAHA.115.306108.
11 Hamrefors V (2015) Common genetic risk factors for coronary artery disease: new opportunities for prevention? Clinical Physiology And Functional Imaging, 17. DOI: 10.1111/cpf.12289.
12 Cole CB, Nikpay M, Stewart AF, McPherson R (2016) Increased genetic risk for obesity in premature coronary artery disease, European Journal of Human Genetics, 24(4):587-91. DOI: 10.1038/ejhg.2015.162.
13 Yamada Y, Matsui K, Takeuchi I, Fujimaki T (2015) Association of genetic variants with coronary artery disease and ischemic stroke in a longitudinal population-based genetic epidemiological study study, Biomedical reports, 3(3), p.413-419.
14 Ozaki K, Tanaka T (2016) Molecular genetics of coronary artery disease, Journal of Human Genetics, 61(1):71-7. DOI: 10.1038/jhg.2015.70.
15 Neelankavil J, Rau CD, Wang Y (2015) The Genetic Basis of Coronary Artery Disease and Atrial Fibrillation: A Search for Disease Mechanisms and Therapeutic Targets, Journal of Cardiothoracic and Vascular Anesthesia, 29(5):1328-32. DOI: 10.1053/j.jvca.2015.01.031. Epub 2015 Jan 23.
16 Hernesniemi JA, Lyytikäinen LP, Oksala N, Seppälä I, Kleber ME, Mononen N, März W, Mikkelsson J, Pessi T, Louhelainen AM, Martiskainen M, Nikus K, Klopp N, Waldenberger M, Illig T, Kähönen M, Laaksonen R, Karhunen PJ, Lehtimäki T (2015) Predicting sudden cardiac death using common genetic risk variants for coronary artery disease, The European Heart Journal, 7;36(26):1669-75. DOI: 10.1093/eurheartj/ehv106.
17 Cheng Y, An B, Jiang M, Xin Y, Xuan S (2015) Association of Tumor Necrosis Factor-alpha Polymorphisms and Risk of Coronary Artery Disease in Patients With Non-alcoholic Fatty Liver Disease, Hepatitis Monthly, 31.15(3), p.26818.
18 Liao B, Cheng K, Dong S, Liu H, Xu Z (2015) Effect of apolipoprotein A1 genetic polymorphisms on lipid profiles and the risk of coronary artery disease, Diagnostic Pathology, 16;10:102. DOI: 10.1186/s13000-015-0328-7.
19 Arslan S, Korkmaz Ö, Özbilüm N, Berkan Ö (2015) Association between NF-κBI and NF-κBIA polymorphisms and coronary artery disease, Biomedical reports, 3(5):736-740.
20 Ahmadi Z, Senemar S, Toosi S, Radmanesh S (2015) The Association of Lipoprotein Lipase Genes, HindIII and S447X Polymorphisms With Coronary Artery Disease in Shiraz City, Journal of Thoracic and Cardiovascular Surgery, 7(2):63-7. DOI: 10.15171/jcvtr.2015.14.
21 Ivashchenko A, Atambayeva S, Niyazova R, Pinsky I (2015) Genes associated with the development of coronary heart disease. Vestnik KazNU, biological series [Geny svyazannye s razvitiem ishemicheskoi bolezni serdtca. Vestnik KazNU, biologicheskaya seriya] 3(65):100-108. (In Russian).
22 Ivashchenko A, Atambayeva S, Niyazova R, Pinsky I (2015) Genes associated with the development of myocardial infarction. Vestnik KazNU, biological series [Geny svyazannye s razvitiem infarcta miocarda. Vestnik KazNU, biologicheskaya seriya] 3(65): 124-132. (In Russian).
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МОЛЕКУЛЯРНАЯ БИОЛОГИЯ И ГЕНЕТИКА
