Antimicrobial properties of extracts Vexibia alopecuroides
136 51
Keywords:
total extracts, fraction, antimicrobial activity.Abstract
Microorganisms Staphylococcus aureus ATCC 29213, Methicillin-resistant S. aureus ATCC 43300, Pseudomonas aeruginosa ATCC 27853, Candida albicans ATTC 90028, Candida krusei ATCC 6258, Candida glabrata ATTC 90030 was used to determine the antimicrobial activity of dichloromethane extracts and alcohol by serial dilution. The extracts were isolated from roots of Vexibia alopecuroides. Samples were collected in the flowering phase in the Almaty region. High antibacterial activity of the extract dichloromethane (concentration of half-maximal inhibition of 3 mg / ml) against Staphylococcus aureus and methicillin - resistant Staphylococcus aureus and the antagonistic effect of biologically active substances in its composition in relation to the yeast Candida Albicans ATTC 90028, Candida krusei ATCC 6258, Candida glabrata ATCC 90030.References
1. Tian A., Xu T., Liu K., Zou Q., Yan X. Anti-helicobacter pylori effect of total alkaloids of sopho-ra alopecuroides in vivo // Chinese Medical Journal.-2014.-Vol. 127(13).-P. 2484-91.
2. Lu X., Lin B., Tang J.G., Cao Z., Hu Y. Study on the inhibitory effect of total alkaloids of Sophora alopecuroides on osteosarcoma cell growth //African Journal of Traditional, Complemen-tary and Alternative Medicines.–2013. -Vol.11, N 1.-P. 172-5.
3. Liu M., Liu X.Y., Cheng J.F. Advance in the pharmacological research on matrine // Zhongguo Zhong Yao Za Zhi. - 2003. –Vol.28. – P. 801-804.
4. Zhang Y.F., Wang S.Z., Li Y.Y., Xiao Z.Y., Hu Z.L., Zhang J.P. Sophocarpine and marine inhib-it the production of TNF and IL-6 in murine macrophages and prevent cachexia-related symptoms induced by colon 26 adenocarcinoma in mice // International Immunopharmacology. - 2008. –Vol. 8. – P. 1767-1772.
5. Lin W., Zhang J.P., Hu Z.L., Qian D.H. Inhibitory effect of matrine on lipopolysacchride induced tumor necrosis factor and interleukin-6 production from rat Kupffer cells // Yao Xue Xue Bao. - 1997. – Vol.32. –P. 93-96.
6. Xing N.L., Sha N., Yan H.X., Pang X.Y., Guan S.H., Yang M., Hua H.M., Wu L.J., Guo D.A. Isoprenylated flavonoids from the roots of Sophora tonkinensis // Phytochemistry Letters. - 2008. – Vol.1. - P.163-167.
7. Bach M.K., Brashler J.R. Inhibition of IgE and compound 48/80-induced histamine release by lectins // Immunology. - 1975. – Vol.29. - P. 371-386.
8. Павлов, Н.В. Флора Казахстана. - Алма-Ата: Академия наук Казахской ССР, 1966. – Т.9
9. Голоскоков В.Р. Иллюстрированный определитель растений Казахстана. - Алма-Ата: Наука, 1969. -Т.1. – 243 с.
10. National Committee for Clinical Laboratory Standards (NCCLS) (Wayne, Pa.): Reference method for broth dilution antifungal susceptibility testing of yeasts; Approved Standard – Second Edition. Document M27-A2.-2002. –P.22 .
11. National Committee for Clinical Laboratory Standards (NCCLS): Methods for dilution antimi-crobial susceptibility test for bacteria that grow aerobically, approved Standard – Seventh edition. Document M7 - A7. -2006. – P.26.
2. Lu X., Lin B., Tang J.G., Cao Z., Hu Y. Study on the inhibitory effect of total alkaloids of Sophora alopecuroides on osteosarcoma cell growth //African Journal of Traditional, Complemen-tary and Alternative Medicines.–2013. -Vol.11, N 1.-P. 172-5.
3. Liu M., Liu X.Y., Cheng J.F. Advance in the pharmacological research on matrine // Zhongguo Zhong Yao Za Zhi. - 2003. –Vol.28. – P. 801-804.
4. Zhang Y.F., Wang S.Z., Li Y.Y., Xiao Z.Y., Hu Z.L., Zhang J.P. Sophocarpine and marine inhib-it the production of TNF and IL-6 in murine macrophages and prevent cachexia-related symptoms induced by colon 26 adenocarcinoma in mice // International Immunopharmacology. - 2008. –Vol. 8. – P. 1767-1772.
5. Lin W., Zhang J.P., Hu Z.L., Qian D.H. Inhibitory effect of matrine on lipopolysacchride induced tumor necrosis factor and interleukin-6 production from rat Kupffer cells // Yao Xue Xue Bao. - 1997. – Vol.32. –P. 93-96.
6. Xing N.L., Sha N., Yan H.X., Pang X.Y., Guan S.H., Yang M., Hua H.M., Wu L.J., Guo D.A. Isoprenylated flavonoids from the roots of Sophora tonkinensis // Phytochemistry Letters. - 2008. – Vol.1. - P.163-167.
7. Bach M.K., Brashler J.R. Inhibition of IgE and compound 48/80-induced histamine release by lectins // Immunology. - 1975. – Vol.29. - P. 371-386.
8. Павлов, Н.В. Флора Казахстана. - Алма-Ата: Академия наук Казахской ССР, 1966. – Т.9
9. Голоскоков В.Р. Иллюстрированный определитель растений Казахстана. - Алма-Ата: Наука, 1969. -Т.1. – 243 с.
10. National Committee for Clinical Laboratory Standards (NCCLS) (Wayne, Pa.): Reference method for broth dilution antifungal susceptibility testing of yeasts; Approved Standard – Second Edition. Document M27-A2.-2002. –P.22 .
11. National Committee for Clinical Laboratory Standards (NCCLS): Methods for dilution antimi-crobial susceptibility test for bacteria that grow aerobically, approved Standard – Seventh edition. Document M7 - A7. -2006. – P.26.
Downloads
How to Cite
Kustova, T. S., Platayeva, A. K., Zavorotnaya, M. V., Karpenyuk, T. A., & Goncharova, A. V. (2016). Antimicrobial properties of extracts Vexibia alopecuroides. Experimental Biology, 65(3), 224–228. Retrieved from https://bb.kaznu.kz/index.php/biology/article/view/1121
Issue
Section
MICROBIOLOGY
