ГЕНЫ СВЯЗАННЫЕ С РАЗВИТИЕМ ИНФАРКТА МИОКАРДА / МИОКАРД ИНФАРКТІСІ ДАМУЫМЕН БАЙЛАНЫСТЫ ГЕНДЕР

A. T. Ivashchenko; Sh. A. Atambayeva; R. Y. Niyazova; I. V. Pinskiy

Authors

A. T. Ivashchenko НИИ проблем биологии и биотехнологии КазНУ им.аль-Фараби
Sh. A. Atambayeva НИИ проблем биологии и биотехнологии КазНУ им.аль-Фараби
R. Y. Niyazova НИИ проблем биологии и биотехнологии КазНУ им.аль-Фараби
I. V. Pinskiy НИИ проблем биологии и биотехнологии КазНУ им.аль-Фараби

Keywords:

myocardial infarction, gene, microRNA, mRNA, diagnostics.

Abstract

The search of the genes-candidates associated with the development of myocardial infarction is conducted. A database of genes associated with the development of myocardial infarction is created and the functions of these genes analyzed in a comparative aspect. It has been shown that many of the genes involved in the development of myocardial infarction associated with the development of other cardiovascular diseases: ischemic heart disease, hypertension, atherosclerosis, metabolic syndrome. Participating of these genes in different social meaningful diseases is analysed. A database of genes associated with the development of myocardial infarction is the basis for the identification of genes which expression is dependent on the action of microRNAs. The features of resulting database of genes and their using in the development of myocardial infarction early diagnostics methods with the help of molecular genetic markers are discussed.