СВОЙСТВА МЕЖГЕННЫХ miRNA ЧЕЛОВЕКА И ОСОБЕННОСТИ ИХ ВЗАИМОДЕЙСТВИЯ С mRNA
Ключевые слова:
взаимодействия, генаралық,Аннотация
Установлены сайты взаимодействия 784 межгенных miRNA с mRNA 52 генов кодирующих интронные miRNA. Выявлены особенности взаимодействия изученных miRNA с 5'UTR, CDS и 3'UTR mRNA каждого гена. Бұл жұмыста 784 генаралық miRNA-дың интронды miRNA кодтайтын 52 геннің mRNA-мен байланысу сайттары анықталды. Зерттелген miRNA-дың əрбір геннің mRNA-ның 5'UTR, CDS жəне 3'UTR-мен байланысу ерекшеліктері зерттелді.Библиографические ссылки
1 Olena A.F. , Patton J.G. Genomic organization of microRNAs // J Cell Physiol. 2010. Vol. 222 (3). P. 540-5
2 Parameswaran P., Sklan E., Wilkins C., Burgon T., Samuel M.A. et al. Six RNA viruses and forty-one hosts:viral small RNAs and modulation of small RNA repertoires in vertebrate and invertebrate systems // PLoS Pathog.,2010. Vol. 6. e1000764.
3 Chabelskaya S., Gaillot O., Felden B. A Staphylococcus aureus small RNA is required for bacterial virulenceand regulates the expression of an immune-evasion molecule // PLoS Pathog., 2010. Vol. 6. e1000927.
4 Braun L., Cannella D., Ortet P., Barakat M., Sautel C.F. et al. A complex small RNA repertoire is generatedby a plant/fungal-like machinery and effected by a metazoan-like argonaute in the single-cell human parasiteToxoplasma gondii // PLoS Pathog., 2010. Vol. 6. e1000920.
5 Parameswaran P., Sklan E., Wilkins C. et.al. Six RNA Viruses and Forty-One Hosts: Viral Small RNAs andModulation of Small RNA Repertoires in Vertebrate and Invertebrate Systems // PLoS Pathog. 2010. Vol. 6(2):e1000764
2 Parameswaran P., Sklan E., Wilkins C., Burgon T., Samuel M.A. et al. Six RNA viruses and forty-one hosts:viral small RNAs and modulation of small RNA repertoires in vertebrate and invertebrate systems // PLoS Pathog.,2010. Vol. 6. e1000764.
3 Chabelskaya S., Gaillot O., Felden B. A Staphylococcus aureus small RNA is required for bacterial virulenceand regulates the expression of an immune-evasion molecule // PLoS Pathog., 2010. Vol. 6. e1000927.
4 Braun L., Cannella D., Ortet P., Barakat M., Sautel C.F. et al. A complex small RNA repertoire is generatedby a plant/fungal-like machinery and effected by a metazoan-like argonaute in the single-cell human parasiteToxoplasma gondii // PLoS Pathog., 2010. Vol. 6. e1000920.
5 Parameswaran P., Sklan E., Wilkins C. et.al. Six RNA Viruses and Forty-One Hosts: Viral Small RNAs andModulation of Small RNA Repertoires in Vertebrate and Invertebrate Systems // PLoS Pathog. 2010. Vol. 6(2):e1000764
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БИОТЕХНОЛОГИЯ, БИОХИМИЯ И ФИЗИОЛОГИЯ РАСТЕНИЙ
