Study of the ability of some essential oils to inhibit influenza virus neuraminidase activity.

Authors

  • N. S. Sokolova РГП «Институт микробиологии и вирусологии» КН МОН РК, г. Алматы
  • A. S. Turmagambetova РГП «Институт микробиологии и вирусологии» КН МОН РК, г. Алматы
  • I. A. Zaitceva РГП «Институт микробиологии и вирусологии» КН МОН РК, г. Алматы
  • M. S. Alexyuk РГП «Институт микробиологии и вирусологии» КН МОН РК, г. Алматы
  • E. S. Moldahkanov РГП «Институт микробиологии и вирусологии» КН МОН РК, г. Алматы
  • K. S. Akanova РГП «Институт микробиологии и вирусологии» КН МОН РК, г. Алматы
  • E. I. Anarkulava РГП «Институт микробиологии и вирусологии» КН МОН РК, г. Алматы
  • A. P. Bogoyavlenskiy РГП «Институт микробиологии и вирусологии» КН МОН РК, г. Алматы
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Keywords:

essential oils, orange, geranium, anti-virus preparations, neuraminidase, flu,

Abstract

The effect of essential oils on the neuraminidase activity of influenza viruses with different antigenic structure was studied. It has been established that the orange or geranium essential oils able to inhibit the enzymatic activity of the influenza virus and, consequently, are involved in inhibiting the infectious activity of influenza virus at the stage output virions from the infected cell. It is shown that the resistance of influenza strains to the action of essential oils depends from neuraminidase subtypes, which may be due to the structural features of the enzyme active site of virus protein. The use of essential oils for the prevention and treatment of influenza may be recommended after a careful study of the composition of essential oils.

References

1 Березин В.Э. Основы вирусологии.– Алматы,2001.– 116 с.
2 Monto A.S. Antivirals and influenza: frequency of resistance // Pediatr. Infect. Dis. J. - 2008.–V.10. Suppl.- P.
S110-122.
3 Киселев О.И., Цыбалова Л.М., Покровский В.И. Грипп: эпидемиология, диагностика, лечение,профилактика. – Москва, 2012. – 18 с.
4 Сюрин В.Н., Белоусова Р.В., Соловьев Б.В. Методы лабораторной диагностики вирусных болезней
животных.- М.: Агропромиздат, 1986.- 303с.
5 Aminoff D. Methods for quantitive estimation of N-acetilneuraminic acid and their application to hydrolisates of
sialomycoides // Biochem. J. – 1961. – V.81. – P.84.

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How to Cite

Sokolova, N. S., Turmagambetova, A. S., Zaitceva, I. A., Alexyuk, M. S., Moldahkanov, E. S., Akanova, K. S., Anarkulava, E. I., & Bogoyavlenskiy, A. P. (2015). Study of the ability of some essential oils to inhibit influenza virus neuraminidase activity. Experimental Biology, 60(2), 343–345. Retrieved from https://bb.kaznu.kz/index.php/biology/article/view/967

Issue

Vol. 60 No. 2 (2014): KazNU Bulletin. Biology series

Section

BIOTECHNOLOGY