The role of tor signaling in the mechanisms of adaptation of Arabidopsis thaliana to salt stress
24 28
Keywords:
Arabidopsis thaliana, TOR, aldehyde oxidase, xanthine dehydrogenase, ABA, salt stressAbstract
TOR (target of rapamycin) kinase is present in most species of higher eukaryotes and plays a key role in the regulation of growth and development of organisms and the formation of the metabolic response of the cell to the action of various stress factors. However, despite the importance TOR signaling in eukaryotes, the physiological mechanisms involving the regulation of this enzyme in plants are still poorly understood. In this paper, was examined the role of TOR kinase in the physiologica mechanisms of adaptation of Arabidopsis thaliana to salt stress by using a mutant line in AtTOR gene. It was found increased activity of aldehyde oxidase and xanthine dehydrogenase in mutant line under salt stress. Based on activity of these enzymes participating in ABA biosynthesis we suggest that TOR kinase can act as a negative factor of ABA biosynthesis regulation under certain conditionsReferences
1 Martin D., Hall M. The expanding TOR signaling network // Curr. Opin. Cell Biol. – 2005. – V.17. – P. 158-166.
2 Bjornsti M., Houghton P. The TOR pathway: A target for cancer therapy // Nature Reviews-Cancer. – 2004. – V. 4.
– P.335–348.
3 Zoncu R., Efeyan A., Sabatini D. mTOR: from growth signal integration to cancer, diabetes and ageing // Nature
Reviews-Molecular Сell Biology. – 2011. – V. 12. – P. 21–35.
4 Sarbassov D., Guertin D., Ali S., Sabatini D. // Phosphorylation and regulation of Akt/PKB by the rictor-mTOR
complex // Science. – 2005. – V. 307. – P.1098-1101.
5 Wullschleger S., Loewith R., Hall M. TOR signaling in growth and metabolism // Cell. – 2006. – V.124. – P. 471–484.
6 Anderson G. TOR signaling in plants // Plant Cell Monographs. – 2008. – V.10. – P.243-259.
7 Moreau M., Sormani R., Menand B.,Veit B., Robaglia C., Meyer C. The TOR complex and signaling pathways in
plants // Enzymes. – 2010. – V.27. – P.285-302.
8 John F., Roffler S., Wicker T., Ringli C. Plant TOR signaling components // Plant Signalling and Behavior. -2011. –V.6. - N.11. – P. 1700-1705.
9 Deprost D., Yao L., Sormani R., Moreau M., Leterreux G., Nicola M., Bedu M., Robaglia C. and Meyer C. The
Arabidopsis TOR kinase links plant growth, yield, stress resistance and mRNA translation // EMBO Rep. – 2007. – V.8. – P. 864–870.
10 Milborrow B.V. The pathway of biosynthesis of abscisic acid in vascular plants: a review of the present state of
knowledge of ABA biosynthesis // Journal of Experimental Botany. – 2001. – V. 52. – P. 1145-1164
.
11 Seo M., Koiwai H., Akaba S., Komano T., Oritani T., Kamiya Y., Koshiba T. Abscisic aldehyde oxidase in leaves of
Arabidopsis thaliana // The Plant Journal. – 2000. – V. 23. – P. 481–488.
2 Bjornsti M., Houghton P. The TOR pathway: A target for cancer therapy // Nature Reviews-Cancer. – 2004. – V. 4.
– P.335–348.
3 Zoncu R., Efeyan A., Sabatini D. mTOR: from growth signal integration to cancer, diabetes and ageing // Nature
Reviews-Molecular Сell Biology. – 2011. – V. 12. – P. 21–35.
4 Sarbassov D., Guertin D., Ali S., Sabatini D. // Phosphorylation and regulation of Akt/PKB by the rictor-mTOR
complex // Science. – 2005. – V. 307. – P.1098-1101.
5 Wullschleger S., Loewith R., Hall M. TOR signaling in growth and metabolism // Cell. – 2006. – V.124. – P. 471–484.
6 Anderson G. TOR signaling in plants // Plant Cell Monographs. – 2008. – V.10. – P.243-259.
7 Moreau M., Sormani R., Menand B.,Veit B., Robaglia C., Meyer C. The TOR complex and signaling pathways in
plants // Enzymes. – 2010. – V.27. – P.285-302.
8 John F., Roffler S., Wicker T., Ringli C. Plant TOR signaling components // Plant Signalling and Behavior. -2011. –V.6. - N.11. – P. 1700-1705.
9 Deprost D., Yao L., Sormani R., Moreau M., Leterreux G., Nicola M., Bedu M., Robaglia C. and Meyer C. The
Arabidopsis TOR kinase links plant growth, yield, stress resistance and mRNA translation // EMBO Rep. – 2007. – V.8. – P. 864–870.
10 Milborrow B.V. The pathway of biosynthesis of abscisic acid in vascular plants: a review of the present state of
knowledge of ABA biosynthesis // Journal of Experimental Botany. – 2001. – V. 52. – P. 1145-1164
.
11 Seo M., Koiwai H., Akaba S., Komano T., Oritani T., Kamiya Y., Koshiba T. Abscisic aldehyde oxidase in leaves of
Arabidopsis thaliana // The Plant Journal. – 2000. – V. 23. – P. 481–488.
Downloads
How to Cite
Bersimbay, P. I., & Kravchenko, A. P. (2015). The role of tor signaling in the mechanisms of adaptation of Arabidopsis thaliana to salt stress. Experimental Biology, 59(3/1), 58–62. Retrieved from https://bb.kaznu.kz/index.php/biology/article/view/646
Issue
Section
Biotechnology: from research to innovations
