Genetic nature of hereditary diseases cattle and molecular genetic methods of diagnosis.
Keywords:
PCR, restriction amplificate, electrophoresis lethal autosomal recessive mutation, BLAD, Citrullinemia,Abstract
This article discusses the role of a point mutation in the etiology of hereditary diseases of cattle, the authors for the detection of genetic defects BLAD, BC, CVM, DUMPS in tribal sires was used polymerase chain reaction and RFLP analysis. Found that domestic breeding bulls are free from harmful genetic mutations.References
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5 Dennis J A, Healy P J, Beaudet A L &O’brien W E Molecular definition of bovine agrininosuccinatesynthetase
deficiency // Proceeding of the National Academy of Sciences. - 1989. – V. 86. – P. 7947-7951.
Biodiverity. - 2010. – Vol. 2. - n 1. – P. 35-41.
2 Яковлев А., Терлецкий В., Митрофанова О., Дементьева Н. Определение носителей генетических дефектов среди быков-производителей // Молочное и мясное скотоводство. – 2004. – Т.6. – С.31-32.
3 Rahimi G., Nejati A., Olek K. Genotyping BLAD DUMPS and k-CSN Loci Holstein Yong Bulls of the National
Animal Breeding Center of Iran // Pakistan Jornal Biological Scienes. - 2006. – V.9(7). – P.1389-1392.
4 Agerholm J S, Bendixen C, Andersen O &Arnbjerg J. Complex vertebral malformation in Holstein calves // Journal of Veterinary Diagnostic Investigation. - 2001. – V. 13. – P. 283-289.
5 Dennis J A, Healy P J, Beaudet A L &O’brien W E Molecular definition of bovine agrininosuccinatesynthetase
deficiency // Proceeding of the National Academy of Sciences. - 1989. – V. 86. – P. 7947-7951.
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