The influence of amino acids on biosynthesis of the antibiotic A-70, active against methicillin-resistant Staphylococci with multiple drug-resistance.

Authors

  • L. P. Trenozhnikova Институт микробиологии и вирусологии КН МОН РК, г. Алматы
  • A. Kh. Khassenova Институт микробиологии и вирусологии КН МОН РК, г. Алматы
  • M. A. Akilova Центральная Клиническая Больница Медицинского Центра Управления Делами Президента РК, г. Алматы
  • G. D. Ultanbekova Институт микробиологии и вирусологии КН МОН РК, г. Алматы
  • Zh. A. Baydyldaeva Институт микробиологии и вирусологии КН МОН РК, г. Алматы

Keywords:

methyl-persistent staphylococcus, antibiotic, biosynthesis, amino-acid,

Abstract

The influence of certain amino acids on the formation of the antibacterial antibiotic-peptolide A-70 was investigated. There was determined the positive influence of valine, glutаmine and phenylalanine on accumulation of the antibiotic A-70 in culture broth: biosynthesis of the antibiotic increased by 11.1-13.3%. Asparagine, arginine, alanine, cysteine, proline, leucine, and lysine inhibit biosynthesis of the antibiotic A-70.

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Issue

Vol. 60 No. 2 (2014): KazNU Bulletin. Biology series

Section

BIOTECHNOLOGY

How to Cite

The influence of amino acids on biosynthesis of the antibiotic A-70, active against methicillin-resistant Staphylococci with multiple drug-resistance. (2015). Experimental Biology, 60(2), 356-359. https://bb.kaznu.kz/index.php/biology/article/view/973

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