Саморегуляция раковых стволовых клеток толстой кишки. Тоқ ішек бағаналы ісік жасушаларының өздігінен реттелуі.

A. S. Issabekova; V. B. Ogay

Colon cancer stem cells self regulation.

Authors

A. S. Issabekova РГП «Национальный центр биотехнологии»
V. B. Ogay РГП «Национальный центр биотехнологии»

Keywords:

colon cancer, cancer stem cells, autocrine inductors, cytokines, growth factors,

Abstract

Colon cancer high death rate and low percentage of recovery depend on tumor initiating cancer stem cells (CSCs). CSCs have ability such as survival in stress condition, absence of sensitivity to apoptose. These properties CSCs can regulate by autocrine way. In our work it was created data base of colon CSCs autocrine inductors. Understanding of CSCs protection mechanisms help to develop effective elimination methods of these cells.