ЭПОХА SARS-COV2 И ПРАВИЛЬНЫЕ СТРАТЕГИИ УПРАВЛЕНИЯ ДЛЯ РЕШЕНИЯ ПРОБЛЕМ КАК В ВИРУСНЫХ ИССЛЕДОВАНИЯХ, ТАК И В ЛЕЧЕНИИ

Авторы

  • С.Ж. Хайдаров Казахский национальный университет имени аль-Фараби, Казахстан, Алматы
  • Е.Д. Бурашев Научно-исследовательский институт проблем биологической безопасности» Министерство Здравоохранения Республики Казахстан

DOI:

https://doi.org/10.26577/eb.2023.v96.i3.01

Ключевые слова:

SARS-COV2, мРНК-геном, ORF (открытые рамки считывания), структурные белки, неструктурные белки (np), классификация вирусов, иммунитет, противовирусные препараты, антитела, IgG, вакцинация и летальный мутагенез. стероиды

Аннотация

SARS - COV2 или COVID-19 вызвали в 2020 году крупнейшую пандемию со времен окончания Первой мировой войны и за относительно короткий период времени нанесли серьезный ущерб мировому здравоохранению и экономике. В этой статье раскрываются вопросы вакцинации путем понимания врожденных и адаптивных иммунных реакций и того, насколько тесно они взаимосвязаны друг с другом. Также необходимо обсудить клеточную и гуморальную части иммунитета и механизмы распознавания связывания рецепторов, нейтрализацию антител и опосредованные антителами как в адаптивном, так и врожденном иммунитете. Стратегии защиты иммунитета являются объектами обсуждения наряду с клиническими случаями и того, насколько эффективной или неэффективной может быть вакцинация с учетом роли антител в создании иммунитета против этого вируса. Эта статья будет интересна тем, кто планирует разрабатывать либо моноклональные исследования, либо стратегии лечения COVID-19 и даже разработку препаратов для вакцинации.

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2023-09-20