Показатели периодического распространения видов возбудителей ренальной инфекции в зависимости от возраста и пола детей по временам года
DOI:
https://doi.org/10.26577/eb.2020.v84.i3.12Аннотация
В статье определены доминирующие типы инфекций, которые вызывают микробное воспаление, которое приводит к повреждению тубулоинтерстициальной ткани и пилоцитарной системы в почках. В исследовании изучены 88 бактериальных культур с мочой детей в возрасте от 1 месяца до 17 лет с ИППП с использованием специальных микробиологических исследований. Проводили секторальную инокуляцию эндо среды и кровяного агара, а видовой состав и количественные параметры кишечной микрофлоры определяли по степени бактериурии. Чувствительность выделенных штаммов микроорганизмов к противомикробным препаратам определяли по стойким маркерам. Методы обработки полученных результатов оценивались с помощью вариационной статистики, достоверности различий анализа по критериям Стьюдента-Фишера. Исследования показали, что стафилококк (30,6%) связан с S. aureus (11,1%). S.epidermidis (48,1%) и S.saprophyticus (37,1 %%), S.intermedius (3,7 o). Доминирующие виды бактериальных культур были также определены, в зависимости от возраста, пола и времени года у детей. Штаммы Coli преобладают летом среди мальчиков и девочек. Enterococcus faecalis распространен осенью, а Candida, родственник гриба, часто встречается у мальчиков зимой. Штамм Staphylococcus epidermidis наиболее распространен среди девочек весной. Были определены чувствительность и устойчивость к антибиотикам штамма Starylococcus eridermidis, наибольшая чувствительность к цефотаксиму (98,6%), цефазолину (97,8%), цефуроксиму (95,5%), амикацину (100%), оксациллину (85,39). имепинем (87,5%). Антибиотикоустойчивость некоторых вид возбудителей мочевыделительной системы у детей, а именно исследуемые условно- патогенные бактерий, также зависят от физиологии отдельного организма.
Ключевые слова: ренальная инфекция, пиелонефрит, микробный биоценоз, бактериурия, тубулоинтерстициальное воспаление, иммунитет
Библиографические ссылки
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19. Dutov V.V, Buimistr S.Iu., Rusanova E.V. (2018). Otsenka bakteriologicheskogo analiza mochi u patsientov s dlitelnym drenirovaniem mochevogo puzyria [Evaluation of bacteriological analysis of urine in patients with prolonged bladder drainage]. Urologiia – Urology, vol. 6, pp. 32-36.
20. Akbar M. (2018). Urologicheskie oslozhneniia posle transplantatsii pochki [Approach to urological complications early post renal transplant]. Klinicheskaia meditsina Kazakhstana - Clinical Medicine of Kazakhstan, vol. 3,no 49, pp. 24-27
21. Goodacre R., Kel D.B. (2017). Commentary on "rapid identification of streptococcus and enterococcus species using diffuse reflectance-absorbance fourier transform infrared spectroscopy and artificial neural networks." FEMS Microbiology Letters, vol. 364(10), pp.1-4
22. Fluer F.S., Loginova O.G., Panova Ia.A.(2019). Chastota vstrechaemosti enterotoksigennykh shtammov Staphylococcus aureus, produtsiruiushchikh enterotoksiny tipov SEC i SEI, vydelennykh pri narushenii kishechnoi mikroflory u detei [The frequency of occurrence of enterotoxigenic strains of Staphylococcus aureus producing enterotoxins of types SEC and SEI isolated in children with intestinal microflora]. Pediatriia - Pediatrics, vol. 98, no 6, pp. 60-64.
23. Li. V., Demichuk L. (2019). Mekhanizmy povrezhdeniia kletok krovi i pochek pri ekzogennykh toksicheskikh nefropatiiakh [Mechanisms of blood cells and kidney lesion in exogenous toxic nephropathies]. Klinicheskaia Meditsina Kazakhstana - Clinical Medicine of Kazakhstan, vol. 51,no1, pp. 60-64.
24. Sizonov V.V., Dubrov V.I., Akramov N.R., Markov N.V, Kagantsov I.M., Shidaev A.Kh-A. (2020). Rezultaty lecheniia novorozhdennykh s postrenalnoi anuriei, obuslovlennoi obstruktsiei bezoarami verkhnikh mochevyvodiashchikh putei [The results of treatment of newborns with postrenal anuria due to obstruction of the upper urinary tract with fungal bezoars]. Pedriatriia i urologiia - Pediatrics and urology, Vol. 1, pp.81-85
25. Palagin I.S., Sukhorukova M.V., Dekhnich A.V., Eidelshtein M.V. (2020). Sostoianie antibiotikorezistentnosti vozbuditelei vnebolnichnykh infektsii mochevyvodiashchikh putei v Rossii, Belorusi i Kazakhstane: rezultaty mnogotsentrovogo mezhdunarodnogo issledovaniia "Darmis-2018"[The status of antibiotic resistance of community-acquired urinary tract infections in Russia, Belarus and Kazakhstan: results of the multicenter international study “Darmis-2018”]. Urologiia – Urology, Vol. 1, pp. 19-31
26. Eveillard M., Pouliquen H., Ruvoen N.,Magras C., Lepelletier D. (2017). Antibiotic exposure and bacterial resistance in human and veterinary medicine: A problem-based learning topic for Master's students. FEMS Microbiology Letters, vol.(6), pp. 361-364
27. Jeukens J., Kukavica-Ibrulj I., Emond-Rheault J.G., Freschi L., Levesque R.C. (2016). Comparative genomics of a drug-resistant pseudomonas aeruginosa panel and the challenges of antimicrobial resistance prediction from genomes. Biochemistry, Genetics and Molecular Biology: Genetics, vol. 364, pp. 18-21
2. Zakharva I.N. (2015) Infektsiia mochevoi sistemy u detei i sovremennye predstavleniia ob etiologii. [Infection of the urinary system in children and modern ideas about the etiology]. Nefrologiia i dializ - Nephrology and dialysis, Vol.1, pp. 48-54
3. Eshimova S., Tulegenova Zh., Kenzhebaeva N., Dinmukhamedova A. (2015). Antibiotikochuvstvitelnost shtammov enterococcus faecalis, vydelennykh ot bolnykh s infektsiiami mochevyvodiashchei sistemy [Antibiotic sensitivity of strains enterococcus faecalis, isolated from patients with urinary tract infections]. Klinicheskaia meditsina Kazakhstana - Clinical Medicine of Kazakhstan, vol. 4, no38, pp.46-49
4. Zhu X.f. Zhang Q.W., Yang S., Zhang D.P. (2017). Candida xinjiangensis sp. nov., a new anamorphic yeast species isolated from Scolytus scheryrewi Semenov in China. Canadian Journal of Microbiology, vol. 199(2), pp.377-383
5. Yang S.C., Fang J.Y., Lin C.H., Aljuffali I.A. (2017). Current pathogenic Escherichia coli foodborne outbreak cases and therapy development. Archives of Microbiology, vol.199(6), pp.811-825
6. Kielak A.M., Cipriano M.A.P., Kuramae E.E. (2016). Acidobacteria strains from subdivision 1 act as plant growth-promoting bacteria. Immunology and Microbiology: Microbiology, vol.198(10), pp.987-993
7. Barabash A.L., Bulgakov N.G. (2015). Vlicianie khimiko-mikrobiologicheskogo sostava podzemnykh pitevykh vod na zdorove cheloveka [The influence of the chemical-microbiological composition of underground drinking water on human health]. Uspekhi sovremennoi biologii - Advances in мodern biology, vol. 2, pp. 480-495
8. Kuznetsova A.A., Revnova M.O., Natochin Yu.V.( 2015). Vodno-solevoy obmen i funktsii pochek u detei pri tseliakii i khronicheskom hastroduodenite [Water-salt metabolism and renal function in children with coeliac disease and chronic gastroduodenitis]. Рediatriya – Pediatrics, vol.2, no5, pp. 27-31.
9. Joseph A.M., Sonowal R., Mahadevan, S. (2017) A comparative study of the evolution of cellobiose utilization in Escherichia coli and Shigella sonnei. Archives of Microbiology., vol. 2, рр. 247-257
10. Yuan Q.B., Huang Y.M., Shen Y., Hu N.( 2018) A comparative study of aeration, biostimulation and bioaugmentation in contaminated urban river purification. Environmental Technology and Innovation., vol. 11, pp. 276-285
11. Klein S.V., Iekoshinina S.A., Sboev A.S. (2016). Prioritetnye faktory riska pitevoi vody i sviazannykh s etim ekonomicheskii ushcherb. [Priority risk factors for drinking water and associated economic damage]. Gigiena i sanitariia - Нygiene and sanitation, vol.1, pp. 10-14
12. Bissenova N., Ergalieva A., Makhambetov K., Talgatbekova N. (2016). Mikrobiologicheskoe obosnovanie effektivnosti probiotika v korrektsii disbakterioza kishechnika [Microbiologic evaluation of efficacy of probiotic for correction intestinal disbiosis]. Klinicheskaia meditsina Kazakhstana- Clinical Medicine of Kazakhstan, vol. 40, no 2, pp. 36-42
13. Pisklakov A.V., Shevliakov A.S. (2016). Pokazateli profilometrii ureterovezikalnogo soustia pri puzyrno-mochetochnikovym refliukse u detei s neirogennoi disfunktsiei mochevogo puzyria [Profilometry of ureterovesical anastomosis in case of vesicoureteral reflux in children with neurogenic bladder dysfunction]. Pediatriia - Pediatrics, vol. 95,no 5, pp. 132-135.
14. Korsunskii A.A., Guseva N.B., Gatkin E.Ia.,Korsunskii I.A. (2017). Kompleksnye lechenie retsidiviruiushchego tsistita pri neirogennoi disfunktsii mochevogo puzyria u devochek [Complex treatment of recurrent cystitis with neurogenic bladder dysfunction in girls]. Pedriatriia – Pediatrics, vol. 96,no1, pp. 209-211
15. Ilyin F.E., Darinsky Yu.A. ( 2017) Ekolohicheskiy monitorinh pitevoi i poverkhnostnykh vod Irtysha i Tobola [Environmental monitoring of drinking and surface waters of the Irtysh and Tobol]. Ekologia cheloveka - Human Ecology, vol. 1,no 1,pp.281-290
16. Tuğcu M., Ruhi C., Gokce A.M., Kara M., Aksaray S. (2017). A case of urinary tract infection caused by Raoultella planticola after a urodynamic study Brazilian. Journal of Infectious Diseases, vol. 21(2), pp.196-198
17. Strydom L., Jewell J., Meier M.A., Pfister B., Zeeman S. (2017). Analysis of genes involved in glycogen degradation in Escherichia coli. FEMS Microbiology Letters, vol. 3, pp.364-368
18. Vasilev A.O., Govorov A.V., Shiriaev A.A. (2018). Izmenenie mikroflory mochi u patsientov s mochekamennoi bolezniu [Changes in the urinary microflora in patients with urolithiasis]. Urologiia – Urology, vol. 6, pp. 26-31.
19. Dutov V.V, Buimistr S.Iu., Rusanova E.V. (2018). Otsenka bakteriologicheskogo analiza mochi u patsientov s dlitelnym drenirovaniem mochevogo puzyria [Evaluation of bacteriological analysis of urine in patients with prolonged bladder drainage]. Urologiia – Urology, vol. 6, pp. 32-36.
20. Akbar M. (2018). Urologicheskie oslozhneniia posle transplantatsii pochki [Approach to urological complications early post renal transplant]. Klinicheskaia meditsina Kazakhstana - Clinical Medicine of Kazakhstan, vol. 3,no 49, pp. 24-27
21. Goodacre R., Kel D.B. (2017). Commentary on "rapid identification of streptococcus and enterococcus species using diffuse reflectance-absorbance fourier transform infrared spectroscopy and artificial neural networks." FEMS Microbiology Letters, vol. 364(10), pp.1-4
22. Fluer F.S., Loginova O.G., Panova Ia.A.(2019). Chastota vstrechaemosti enterotoksigennykh shtammov Staphylococcus aureus, produtsiruiushchikh enterotoksiny tipov SEC i SEI, vydelennykh pri narushenii kishechnoi mikroflory u detei [The frequency of occurrence of enterotoxigenic strains of Staphylococcus aureus producing enterotoxins of types SEC and SEI isolated in children with intestinal microflora]. Pediatriia - Pediatrics, vol. 98, no 6, pp. 60-64.
23. Li. V., Demichuk L. (2019). Mekhanizmy povrezhdeniia kletok krovi i pochek pri ekzogennykh toksicheskikh nefropatiiakh [Mechanisms of blood cells and kidney lesion in exogenous toxic nephropathies]. Klinicheskaia Meditsina Kazakhstana - Clinical Medicine of Kazakhstan, vol. 51,no1, pp. 60-64.
24. Sizonov V.V., Dubrov V.I., Akramov N.R., Markov N.V, Kagantsov I.M., Shidaev A.Kh-A. (2020). Rezultaty lecheniia novorozhdennykh s postrenalnoi anuriei, obuslovlennoi obstruktsiei bezoarami verkhnikh mochevyvodiashchikh putei [The results of treatment of newborns with postrenal anuria due to obstruction of the upper urinary tract with fungal bezoars]. Pedriatriia i urologiia - Pediatrics and urology, Vol. 1, pp.81-85
25. Palagin I.S., Sukhorukova M.V., Dekhnich A.V., Eidelshtein M.V. (2020). Sostoianie antibiotikorezistentnosti vozbuditelei vnebolnichnykh infektsii mochevyvodiashchikh putei v Rossii, Belorusi i Kazakhstane: rezultaty mnogotsentrovogo mezhdunarodnogo issledovaniia "Darmis-2018"[The status of antibiotic resistance of community-acquired urinary tract infections in Russia, Belarus and Kazakhstan: results of the multicenter international study “Darmis-2018”]. Urologiia – Urology, Vol. 1, pp. 19-31
26. Eveillard M., Pouliquen H., Ruvoen N.,Magras C., Lepelletier D. (2017). Antibiotic exposure and bacterial resistance in human and veterinary medicine: A problem-based learning topic for Master's students. FEMS Microbiology Letters, vol.(6), pp. 361-364
27. Jeukens J., Kukavica-Ibrulj I., Emond-Rheault J.G., Freschi L., Levesque R.C. (2016). Comparative genomics of a drug-resistant pseudomonas aeruginosa panel and the challenges of antimicrobial resistance prediction from genomes. Biochemistry, Genetics and Molecular Biology: Genetics, vol. 364, pp. 18-21
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Как цитировать
Yeleupayeva, S. K., & Dinmukhamedova, A. S. (2020). Показатели периодического распространения видов возбудителей ренальной инфекции в зависимости от возраста и пола детей по временам года. Вестник КазНУ. Серия биологическая, 84(3), 130–140. https://doi.org/10.26577/eb.2020.v84.i3.12
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Раздел
ФИЗИОЛОГИЯ ЧЕЛОВЕКА И ЖИВОТНЫХ
